ADRENOCORTEX

Comprehensive Salivary Hormone Test for Stress, Cortisol & DHEA Balance

The Adrenocortex Stress Profile (ASP) is a comprehensive salivary hormone test designed to evaluate your body’s Hypothalamic-Pituitary-Adrenal (HPA) axis and overall stress response. By measuring key stress hormones—cortisol and DHEA—at multiple points throughout the day, this profile reveals your natural diurnal hormone rhythm and provides insights into adrenal function and resilience to daily stressors.

Benefits & Clinical Insights

This profile provides clear, actionable insight into how the body responds to stress, helping both patients and clinicians better understand adrenal function and daily hormone rhythms. By identifying abnormal cortisol patterns that may disrupt sleep, energy levels, or mood, the test supports a deeper evaluation of how stress impacts long-term health. Results can guide personalized care plans focused on stress management, lifestyle modifications, and targeted nutritional or adaptogen support. When used over time, the profile also allows progress to be monitored, helping optimize recovery and improve stress resilience. Many individuals experience improved energy, mental clarity, emotional balance, and more restorative sleep once identified imbalances are addressed.

How the Test Works

Using non-invasive saliva samples, the Adrenocortex Stress Profile measures:

01

Cortisol, the primary stress hormone, at four specific times over a 24-hour period

02

DHEA, a hormone that helps balance metabolism and supports anabolic processes

03

A cortisol-to-DHEA ratio to assess the balance between catabolic and anabolic activity in the body

An optional add-on, the Cortisol Awakening Response (CAR), includes additional morning samples to evaluate how well your HPA axis responds to anticipated challenges.

Who Should Consider This Test?

Persistent stress and HPA axis dysfunction can contribute to a range of symptoms and health issues. The Adrenocortex Stress Profile is particularly useful for individuals experiencing:



  • Chronic fatigue, poor stress tolerance, or burnout
  • Sleep disturbances such as insomnia
  • Mood issues including anxiety or depression
  • Weight management struggles or metabolic concerns
  • Hormone imbalances that affect energy and recovery


Because cortisol and DHEA influence immune function, metabolism, and overall well-being, this test helps uncover hidden imbalances that standard blood tests may miss.

Who Should Consider This Test?

Persistent stress and HPA axis dysfunction can contribute to a range of symptoms and health issues. The Adrenocortex Stress Profile is particularly useful for individuals experiencing:



  • Chronic fatigue, poor stress tolerance, or burnout
  • Sleep disturbances such as insomnia
  • Mood issues including anxiety or depression
  • Weight management struggles or metabolic concerns
  • Hormone imbalances that affect energy and recovery


Because cortisol and DHEA influence immune function, metabolism, and overall well-being, this test helps uncover hidden imbalances that standard blood tests may miss.

Testing Experience & Results

The Adrenocortex Stress Profile:


  • Uses simple at-home saliva collection
  • Does not require blood draws or clinic visits
  • Includes an easy-to-interpret graphic report showing your hormone patterns
  • Offers additional support materials and guidance for sample collection and result interpretation


Your test results can be shared with your healthcare provider to guide tailored interventions and promote long-term health improvements.

Schedule An Appointment

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